What is Amiodarone?
Amiodarone is classed as an anti arrhythmic drug which can be used to treat irregular heartbeats and ventricular tachycardia.
How does it work?
A heart beat is stimulated by electrical signals which come from cells in the heart. An arrhythmia is caused when these regular signals are disrupted. Amiodarone acts on these cells to slow down the disordered electrical signals that cause these irregular heart rhythms.
How to take Amiodarone?
Amiodarone is often started at a relatively high dose for a short period of time to achieve the optimal level in the body. Usually this would mean taking amiodarone three times daily for one week, then two times daily for a further week then once daily thereafter. Note, the dose and frequency of the medication may be different for each patient so ensure you follow the instruction of your clinician.
What to do if I miss a dose?
If you miss a dose take this as soon as you remember. When you are on regular once daily treatment, if you remember within 12 hours of your next dose then omit the dose and continue medication as normal when the next dose is due. Never take a double dose to make up for a missed dose.
Side effects
Like any medication, amiodarone can cause side effects. Not everyone will experience these effects but if you have any concerns contact your doctor or pharmacist. The following are some of the potential side effects of your medication:
Eyes
Amiodarone can cause small deposits on the surface of the eye which could cause some changes in your vision. Some patients describe seeing a blue halo around light sources and can be more dazzled by bright lights at night, hence caution is advised when driving in the dark. These deposits are not harmful and not a reason to stop treatment but if you do experience these effects then inform your optician. Whilst on this medication ensure to attend your annual eye test.
Skin
Amiodarone has been known to cause increased sensitivity to sunlight. Whilst taking this medication ensure to use SPF 30 or higher when out in the sunshine and cover up where possible. Amiodarone stays in the body for several months after you stop taking it, therefore, you need to continue to be mindful of sun exposure until this clear out period has ended.
Liver
Amiodarone can very rarely cause problems with the liver. Liver function will be monitored every 6 months with blood tests. If you experience any of the following seek medical attention: yellowing of the skin or eyes, dark urine or pale stools.
Lungs
Amiodarone can rarely cause lung problems. If you develop new shortness of breath or a persistent cough contact your GP.
Thyroid
Due to the iodine content of amiodarone this can have an effect on the function of your thyroid. This can cause the thyroid gland to become over or underactive. Signs to look out for are listed below, if you develop these symptoms when taking amiodarone then contact your GP:
Hypothyroid
- Tiredness
- Weight gain
- Low mood
- Constipation
- Dry skin
- Sensitivity to the cold
Hyperthyroid
- Anxiety
- Palpitations
- Weight loss
- Trouble sleeping
- Sensitivity to the heat
Should I avoid any medications or foods when taking amiodarone?
Amiodarone can interact with other medications, therefore ensure you inform your doctor or pharmacist when starting any new medication. It is advised to avoid grapefruit juice whilst taking amiodarone as this can increase the levels of amiodarone in the body.
Monitoring requirements and tests
Whilst taking this medication you will be reviewed every 6 months by your doctor. You will need blood tests before this appointment which will assess the function of your thyroid and liver. Additionally you will need to attend annual eye check-ups with your optician.
