Fludrocortisone causes ‘salt’ (sodium) retention via the kidneys. This leads to retention of water and an increase in overall blood volume. Alongside adequate fluid intake, this may reduce or eliminate episodes of low blood pressure.
Fludrocortisone can be used in patients with Orthostatic Hypotension or Vasovagal Syncope when conservative measures are insufficient to relieve symptoms.
It is important to continue conservative measures while taking Fludrocortisone:
- Drink at least 1.5 – 2 litres of water before 2pm each day
- Add salt to your diet if advised to do so in the clinic
- Physical counter manoeuvres (tightening lower limb muscles) for acute symptom relief
Please ensure you read the medication information leaflet carefully prior to taking it.
It is unknown whether Fludrocortisone causes harm to an unborn child.
Please notify your doctor
- If you are pregnant, planning to become pregnant or are breast-feeding
- If you are taking prescription or non-prescription drugs, herbal preparations, or dietary supplements
Dose
It is prescribed once a day, in doses of 50 to 300 micrograms.
Fludrocortisone should be stored in the fridge.
Side-effects:
Fludrocortisone is usually well tolerated; the main side effects are listed below
- Swelling due to fluid retention
- High blood pressure
- Headache
- Low blood potassium level
Weaning Fludrocortisone
It is important not to discontinue fludrocortisone abruptly. It must be weaned under medical supervision, please ensure this is done by your GP or the Falls and Syncope Service.
Precautions
Please notify your doctor if you have any of the following conditions:
- Glaucoma
- Cataracts
- High blood pressure
Please ensure your doctor is aware of all the medications you are currently taking, both prescription and non-prescription.
Secretary Tel: 0191 445 3843